In animal studies, piperine also inhibited other enzymes important in drug
metabolism By inhibiting drug metabolism, piperine may increase the bioavailability
of various compounds and alter the effectiveness of some medications.
piperine may enhance bioavailability of curcumin by
2000% in humans The exact mechanism of piperine's bioavailability enhancing
abilities is unknown.
Chemopreventive efficacy of curcumin and piperine has been
shown during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch
Recently the journal Molecular Nutrition Food Research published
evidence that piperine can enhance the pharmacokinetic parameters of
resveratrol via inhibiting its glucuronidation,
thereby slowing its elimination.
In February 2008, researchers discovered that piperine can stimulate
pigmentation in the skin, together with the exposure to UVB light
Piperine has shown 'anti-depression like activity', and cognitive enhancing
effects in rats
Piperine has shown anti-inflammatory and anti-arthritic effects in human
interleukin-1beta-stimulated fibroblast-like synoviocytes and in rat arthritis
A bit technical, but it explains how piperine works in a chemical way. I have also included links that explains some of the big words.
Piperine is found in black pepper, so by including black pepper in your diet you can enhance other spices that you use.
Piperine has its own anti-inflammatory properties so when used with Turmeric they complement and enhance each other